The current regulatory program for dissolved salts (represented primarily by chloride, sulfate, and TDS) presents significant challenges for water resource managers in both the water and wastewater fields. The objective of the following comments is to provide the Texas Commission on Environmental Quality (TCEQ) with information that will assist with the development of procedures to assess dissolved salts that are environmentally sound, protective of human health, and also take into consideration current and best available science and technology.